Organising metabolic networks: cycles in flux distributions
Metabolic networks are among the most widely studied biological systems. The topology and interconnections of metabolic reactions have been well described for many species, but are not sufficient t…
Received 02 November 2009 16:01 UTC; Posted 02 November 2009
Posted to: Bioinformatics
Reconstruction of an in silico metabolic model of Arabidopsis thaliana through database integration
The number of genome-scale metabolic models has been rising quickly in recent years, and the scope of their utilization encompasses a broad range of applications from metabolic engineering to biolo…
Received 02 June 2009 17:33 UTC; Posted 03 June 2009
Posted to: Bioinformatics
Local and global modes of drug action in biochemical networks
It becomes increasingly accepted that a shift is needed from the traditional target-based approach of drug development to an integrated perspective of drug action in biochemical systems. We here pr…
Received 13 November 2008 15:22 UTC; Posted 14 November 2008
Posted to: Biotechnology