Specificity and Evolvability in Eukaryotic Protein Interaction Networks
Progress in uncovering the protein interaction networks of several species has led to questions of what underlying principles might govern their organization. Few studies have tried to determine th…
Received 28 February 2007 20:11 UTC; Posted 02 March 2007
Posted to: Bioinformatics, Evolutionary Biology
Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions
Protein interaction networks are an important part of the post-genomic effort to integrate a part-list view of the cell into system-level understanding. Using a set of 11 yeast genomes we show that…
Received 19 January 2007 11:36 UTC; Posted 19 January 2007
Posted to: Ecology, Bioinformatics, Evolutionary Biology
The likelihood that two proteins interact might depend on the proteins’ age
It has been previously shown [1] that S. cerevisiae proteins preferentially interact with proteins of the same estimated likely time of origin. To study this observation further, the protein int…
Received 22 January 2007 19:19 UTC; Posted 22 January 2007
Posted to: Bioinformatics, Evolutionary Biology
