Wei Zhang
Estimation of DNA Sequence Context-dependent Mutation Rates Using Primate Genomic Sequences: Application to Estimation of Selection Bias in Protein (Human TP53) Evolution
Understanding of the mechanism of DNA mutation process is critical for studying the functional consequences of genetic variation in clinical medicine (eg. drug response) as well as other complex tr…
Received 19 October 2007 18:28 UTC; Posted 23 October 2007
Posted to: Ecology, Bioinformatics, Evolutionary Biology
A Handy Script to Implement Genetic Models in R
Genome-wide associations between genotypic and phenotypic data often assume certain genetic models. A handy script in R was written to implement three commonly used genetic models: additive, domina…
Received 04 February 2008 17:10 UTC; Posted 05 February 2008
Posted to: Bioinformatics