http://precedings.nature.com/users/bd07eb06af8110721e78b4a2efbb5ec7/ Documents posted by Bell Eapen Nature Publishing Group en Nature Precedings http://precedings.nature.com/images/header_logo.gif http://precedings.nature.com http://precedings.nature.com/documents/2931/version/1 Delayed type hypersensitivity to natural rubber latex is rare compared to IgE mediated immediate reactions. Binding of allergens to MHC Class II is a crucial step in the presentation of antigens to CD4+ T Cells responsible for delayed reactions. Computational prediction of MHC class II epitopes on thirteen known latex allergens using SMM-align method revealed strong binding with several alleles. This shows that latex allergens are capable of initiating delayed type hypersensitivity in susceptible individuals. http://precedings.nature.com/documents/2931/version/1 Fri, 06 Mar 2009 10:34:39 UTC Delayed-Type hypersensitivity to latex: Computational prediction of MHC class II epitopes on latex allergens hdl:10101/npre.2009.2931.1 2009-03-06 Bell R. Eapen Nature Precedings 2009-03-06T10:34:39Z Manuscript Immunology Bioinformatics http://creativecommons.org/licenses/by/3.0/