stephan persengiev
Activation of TRF3 Transcription Factor by Small Interfering RNAs
RNA interference (RNAi) is a conserved biological response to double-stranded RNAs that results in posttranscriptional silencing of target gene expression. Double-stranded processed RNAs of 21-23 n…
Received 04 October 2007 06:58 UTC; Posted 04 October 2007
Posted to: Molecular Cell Biology
Induction of Stress Granule Assembly is Essential for the Orchestration of DNA Damage Response
DNA damage provokes several responses including DNA repair, cell cycle regulation and apoptosis that collectively represent the DNA damage response (DDR). Here, we demonstrate that the DDR incorpor…
Received 13 February 2008 08:38 UTC; Posted 15 February 2008
Posted to: Molecular Cell Biology
Proapoptotic Bid Association with Mre11-Rad50-Nbs1 Complex is Indispensable for Checkpoint Activation after DNA Damage
The proapoptotic protein Bid is phosphorylated by ATM after double strand breaks (DSBs) induction and induces S-phase arrest by a mechanism that remains to be elucidated. Here we show that in mamma…
Received 03 October 2007 13:09 UTC; Posted 03 October 2007
Posted to: Cancer, Molecular Cell Biology
