martin piskacek
9aaTAD Prediction result (2006)
Recently reported, 9aaTAD transcription factors p53, VP16, MLL/ALL, E2A, HSF1, NF-IL6, NFAT1 and NF-kB interact directly with the general coactivator CBP/p300 aside from already referred TAF9. All …
Received 18 November 2009 15:27 UTC; Posted 20 November 2009
Posted to: Genetics & Genomics
Rsp5 promotes Gene Activation mediated by 9aaTAD Transcription Factors Oaf1 and Gal4
Nine-amino-acid transactivation domain, 9aaTAD, defines a large superfamily of yeast and mammals transcription factors. The transactivation of the 9aaTAD has been addressed to multiple general co-a…
Received 11 November 2009 23:04 UTC; Posted 16 November 2009
Posted to: Genetics & Genomics, Molecular Cell Biology
9aaTADs mimic DNA to interact with a pseudo-DNA Binding Domain KIX of Med15 (Molecular Chameleons)
The KIX-domain of Gal11/MED15 was shown to interact with short transactivation domain of Pdr1 and Oaf1 (12 and 9 amino acids respectively) annotated to 9aaTAD family. Reported NMR data revealed a s…
Received 03 November 2009 21:11 UTC; Posted 05 November 2009
Posted to: Genetics & Genomics
Common Transactivation Motif 9aaTAD recruits multiple general co-activators TAF9, MED15, CBP and p300
More than 2000 transcription factors are involved in the human gene regulation to provide cellular function and development. Transactivation domain, TAD, mediates the interaction of transcription f…
Received 03 November 2009 12:30 UTC; Posted 05 November 2009
Posted to: Genetics & Genomics
