Xiaolong Wang
Polymerase-endonuclease amplification reaction for large-scale enzymatic production of antisense oligonucleotide
Synthetic oligonucleotides are contaminated with highly homologous failure sequences. Oligonucleotide synthesis is difficult to scale up because it requires expensive equipments, hazardous chemical…
Received 02 September 2009 04:00 UTC; Posted 02 September 2009
Posted to: Biotechnology, Chemistry, Pharmacology