Tohru Hasegawa
Homocysteic acid as a pathogen for Alzheimer’s disease
It has been considered that Alzheimer’s disease may be induced by multi-pathogenic factors. However recent Nature Genetics has reported that sporadic Alzheimer’s disease is also genetically determ…
Received 09 September 2009 10:12 UTC; Posted 09 September 2009
Posted to: Neuroscience
Dissociation of Alzheimer’s morphological pathology from cognitive impairment
We observed the Alzheimer’s morphological pathology, amyloid production induces Alzheimer’s cognitive impairment, was dissociated from the cognitive impairment. The earlier Alzheimer’s pathological…
Received 13 March 2009 04:40 UTC; Posted 17 March 2009
Posted to: Neuroscience
B6 deficient feeding or homocysteic acid induces the earlier Alzheimer’s pathological change in normal C57BL male mice
It is the first report that the earlier Alzheimer’s pathological changes can be induced in normal C57BL mice, by B6 deficient feeding for 3 month, and this pathological changes were completely inhi…
Received 08 January 2009 08:34 UTC; Posted 12 January 2009
Posted to: Neuroscience
Treatment of Alzheimer’s Disease with Anti-Homocysteic acid Antibody
Homocysteic acid (HA) may play an important role in Alzhiemer disease (AD) as we previously reported that HA induced accumulation of intraneuronal Aβ42. In this study, we first analyzed HA lev…
Received 26 September 2008 15:23 UTC; Posted 30 September 2008
Posted to: Neuroscience
