http://precedings.nature.com/users/837dbbbbfc6edaa6e7c750b81819ba88/ Documents posted by alexander garcia Nature Publishing Group en Nature Precedings http://precedings.nature.com/images/header_logo.gif http://precedings.nature.com http://dx.doi.org/10.1038/npre.2009.3590.2 Lipids can be systematically classified according to functional properties, structural features, biochemical origin or biological system. However Lipid nomenclature has yet to become a robust research tool since no rigorous definitions exist for membership of specific lipid classes. Lipids need to be defined in a manner that is systematic yet at the same time semantically explicit. We report on the reuse of existing lipid nomenclature, ontology describing chemical structure and the extension of the OWL-DL Lipid Ontology to support the classification of lipid molecules. We applied definitions, DL-axioms, to describe lipids classes and illustrate suitability of the ontology for the classification of Fatty Acyl lipids and Mycolic acids. http://dx.doi.org/10.1038/npre.2009.3590.2 Wed, 12 Aug 2009 21:13:51 UTC An OWL-DL Ontology for Classification of Lipids doi:10.1038/npre.2009.3590.2 2009-08-12 Hong-Sang Low Nature Precedings 2009-08-12T21:13:51Z Presentation Chemistry Bioinformatics http://creativecommons.org/licenses/by/3.0/ http://precedings.nature.com/documents/3542/version/1 Lipids can be systematically classified according to functional properties, structural features, biochemical origin or biological system. However Lipid nomenclature has yet to become a robust research tool since no rigorous definitions exist for membership of specific lipid classes. Lipids need to be defined in a manner that is systematic yet at the same time semantically explicit. We report on the reuse of existing lipid nomenclature, ontology describing chemical structure and the extension of the OWL-DL Lipid Ontology to support the classification of lipid molecules. We applied definitions, DL-axioms, to describe lipids classes and illustrate suitability of the ontology for the classification of Fatty Acyl lipids and Mycolic acids. http://precedings.nature.com/documents/3542/version/1 Mon, 03 Aug 2009 14:16:25 UTC An OWL-DL Ontology for Classification of Lipids hdl:10101/npre.2009.3542.1 2009-08-03 Christopher J. O. Baker Nature Precedings 2009-08-03T14:16:25Z Manuscript Chemistry Bioinformatics http://creativecommons.org/licenses/by/3.0/ http://precedings.nature.com/documents/3231/version/1 This paper addresses two research questions: “How should a well-engineered methodology facilitate the development of ontologies within communities of practice?” and “What methodology should be used?” If ontologies are to be developed by communities then the ontology development life cycle should be better understood within this context. This paper presents the Melting Point (MP), a proposed new methodology for developing ontologies within decentralized settings. It describes how MP was developed by taking best practices from other methodologies, provides details on recommended steps and recommended processes, and compares MP with alternatives. The methodology presented here is the product of direct first-hand experience and observation of biological communities of practice in which some of the authors have been involved. The Melting Point is a methodology engineered for decentralised communities of practice for which the designers of technology and the users may be the same group. As such, MP provides a potential foundation for the establishment of standard practices for ontology engineering. http://precedings.nature.com/documents/3231/version/1 Fri, 08 May 2009 09:47:22 UTC Developing ontologies in decentralised settings hdl:10101/npre.2009.3231.1 2009-05-08 Frank Gibson Nature Precedings 2009-05-08T09:47:22Z Manuscript Bioinformatics http://creativecommons.org/licenses/by/3.0/