Sandra Dessi
4 votes
In vitro synergistic anti-prion effect of cholesterol ester modulators
Background. Our studies on the role of cholesterol in prion infection/replication showed that brains and peripheral cells of sheep susceptible to or suffering from Scrapie were characterized by an …
Received 21 October 2009 13:06 UTC; Posted 21 October 2009
Posted to: Microbiology, Neuroscience, Pharmacology
5 votes
Altered cholesterol ester cycle in ex vivo skin fibroblasts from Alzheimer patients
Recent studies in both animal and cell models of Alzheimer’s disease (AD) indicated that sub-cellular cholesterol distribution seems to regulate amyloid-beta (Aβ) generation in the brain. In p…
Received 18 February 2008 17:15 UTC; Posted 19 February 2008
Posted to: Molecular Cell Biology, Neuroscience
