Rosario Marretta
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Optimal control circuitry design for the digital p53 dynamics in cancer cell and apoptosis
Experimental work and theoretical models deduce a “digital” response of the p53 transcription factor when genomic integrity is damaged. The mutual influence of p53 and its antagonist, the Mdm2 onco…
Received 13 February 2009 00:02 UTC; Posted 17 February 2009
Posted to: Biotechnology, Cancer, Developmental Biology
