Michael Baker
Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-induced Suppression of Cytokine Production
Background. Organotins are highly toxic and widely distributed environmental chemicals. Dibutyltin (DBT) is used as stabilizer in the production of polyvinyl chloride plastics, and it is also the m...
Received 18 September 2008 17:41 GMT; Posted 19 September 2008
Posted to: Immunology, Pharmacology, Bioinformatics
Trichoplax, the simplest known animal, contains an estrogen-related receptor but no estrogen receptor: Implications for estrogen receptor evolution
Although, as their names imply, estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to each other are not fully unders...
Received 12 August 2008 01:36 GMT; Posted 13 August 2008
Posted to: Developmental Biology, Evolutionary Biology and Ecology, Bioinformatics
Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors
Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to eac...
Received 06 May 2008 21:36 GMT; Posted 06 May 2008
Posted to: Developmental Biology, Evolutionary Biology and Ecology, Bioinformatics
Motif analysis of amphioxus, lamprey and invertebrate estrogen receptors and amphioxus and human estrogen-related receptors: Towards a better understanding of estrogen receptor evolution
Background. The origins of steroid-dependent regulation of the vertebrate estrogen receptor (ER) are poorly understood. Genes with statistically significant sequence similarity to vertebrate ERs ...
Received 11 April 2008 21:19 GMT; Posted 14 April 2008
Posted to: Cancer, Developmental Biology, Evolutionary Biology and Ecology, Bioinformatics