Henry Niman
Aggregation of Single Nucleotide Polymorphisms in a Human H5N1 Clade 2.2 Hemagglutinin
The rapid evolution of the H5N1 serotype of avian influenza has been explained by a mechanism involving the selection of single nucleotide polymorphisms generated by copy errors. The recent emerge…
Received 10 September 2007 09:26 UTC; Posted 12 September 2007
Posted to: Genetics & Genomics, Evolutionary Biology
Emergence and Fixing of Antiviral Resistance in Influenza A Via Recombination and Hitch Hiking
The dramatic rise of oseltamivir resistance in the H1N1 serotype in the 2007/2008 season and the fixing of H274Y in the 2008/2009 season has raised concerns regarding individuals at risk for season…
Received 29 January 2009 21:07 UTC; Posted 10 February 2009
Posted to: Biotechnology, Genetics & Genomics, Immunology
Swine Influenza A Evolution via Recombination – Genetic Drift Reservoir
The looming influenza pandemic has focused attention1-4 on the rapid evolution of H5N1 and other human and avian serotypes. The basic tenets of influenza genetics5 define gradual changes as dr…
Received 07 July 2007 03:02 UTC; Posted 10 July 2007
Posted to: Ecology, Genetics & Genomics
Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1,2. The number of confirmed human cases now exceeds 300 and the …
Received 07 May 2008 22:53 UTC; Posted 08 May 2008
Posted to: Biotechnology, Ecology, Genetics & Genomics, Microbiology, Bioinformatics
H5N1 Clade 2.2 Polymorphism Tracing Identifies Influenza Recombination and Potential Vaccine Targets
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1. The number of confirmed human cases now exceeds 300 and the as…
Received 07 August 2007 17:32 UTC; Posted 07 August 2007
Posted to: Biotechnology, Ecology, Genetics & Genomics, Microbiology, Bioinformatics
