Diagnostic robustness of DNA microarrays in the classification of acute leukemia
Countless statistical methods have been described for the analysis of DNA microarrays, and each yields distinct results. This raises the question whether DNA microarrays are robust diagnostic tools…
Received 20 September 2007 15:34 UTC; Posted 26 September 2007
Posted to: Biotechnology, Cancer, Genetics & Genomics, Molecular Cell Biology, Pharmacology, Bioinformatics
DNA expression microarrays may be the wrong tool to identify biological pathways
DNA microarray expression signatures are expected to provide new insights into patho- physiological pathways. Numerous variant statistical methods have been described for each step of the signal an…
Received 18 September 2007 13:09 UTC; Posted 19 September 2007
Posted to: Biotechnology, Genetics & Genomics, Molecular Cell Biology, Pharmacology, Bioinformatics