3 votes
Optimization of the Ugi reaction using parallel synthesis and automated liquid handling
The Ugi reaction has proved to be a convenient way to quickly create diverse libraries of compounds. It involves the reaction of an amine, an aldehyde, a carboxylic acid and an isonitrile typically…
Received 27 August 2008 20:56 UTC; Posted 29 August 2008
Posted to: Chemistry, Pharmacology
8 votes
Chemistry Crowdsourcing and Open Notebook Science
This is a pre-proposal written for the NSF program CDI (Cyber-Enabled Discovery and Innovation) in Jan 2008.The current system of dissemination of scientific data and knowledge is far less eff…
Received 09 January 2008 19:29 UTC; Posted 10 January 2008
Posted to: Cancer, Chemistry, Bioinformatics
