Peter Natesan Pushparaj
Genome activity profiling of monomeric-IgE and Fc-epsilon-RI-aggregation on human mast cells reveals a complex network of genes involved in inflammatory responses.
Mast cell activation, mediates type-1 allergic responses, one of the most powerful reactions of the immune system. However, mast cells activation is becoming increasingly linked to inflammatory, au...
Received 27 September 2007 14:50 GMT; Posted 28 September 2007
Posted to: Immunology, Molecular Cell Biology, Pharmacology, Bioinformatics
Differences in the gene expression profile of human monocytic cells activated by high and low affinity Fc-gamma-receptors.
Receptors for the constant (Fc) region of immunoglobulin G, play an important role in linking the humoral and cellular arms of immune response. Three different classes of receptors have been define...
Received 27 September 2007 14:42 GMT; Posted 28 September 2007
Posted to: Immunology, Molecular Cell Biology, Bioinformatics
Differential Gene Expression of Human Mast cell Activation Reveals Gene profiles of Innate and Adaptive Immunity.
High-density oligonucleotide microarray is a promising approach for high throughput analysis. It has been extensively used in many areas of biomedical research. Immunoglobulin E (IgE) mediated alle...
Received 27 September 2007 14:37 GMT; Posted 28 September 2007
Posted to: Immunology, Molecular Cell Biology, Pharmacology, Bioinformatics
siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy.
Systemic anaphylaxis is considered to be a typical immediate hypersensitivity response, determined by the activation of immune cells,via antigen-induced aggregation of IgE-sensitized FcεRI cells. P...
Received 27 September 2007 14:31 GMT; Posted 27 September 2007
Posted to: Immunology, Molecular Cell Biology, Pharmacology
The Immune Response in Patients with SARS: differential gene expression profiling.
Severe acute respiratory syndrome (SARS) emerged in 2003, as a new epidemic form of life-threatening infection. As of 26th September 2003, there were 8422 cases of SARS from 29 countries with 908 d...
Received 27 September 2007 14:19 GMT; Posted 27 September 2007
Posted to: Immunology, Molecular Cell Biology, Bioinformatics