Submissions tagged with yeast
(8 documents)
The joys and perils of recombination – The hotspot conversion paradox and the evolution of recombination
The contradiction between the long-term persistence of the chromosomal hotspots that initiate meiotic recombination and the self-destructive mechanism by which they act strongly suggests that our u…
Received 21 August 2009 20:11 UTC; Posted 21 August 2009
Posted to: Genetics & Genomics, Evolutionary Biology
The hotspot conversion paradox
The contradiction between the long-term persistence of the chromosomal hotspots that initiate meiotic recombination and the self-destructive mechanism by which they act strongly suggests that our u…
Received 17 August 2009 20:07 UTC; Posted 18 August 2009
Posted to: Genetics & Genomics, Evolutionary Biology
Yeast Features: Identifying Significant Features Shared Among Yeast Proteins for Functional Genomics
BackgroundHigh throughput yeast functional genomics experiments are revealing associations among tens to hundreds of genes using numerous experimental conditions. To fully understand how the iden…
Received 18 September 2008 23:22 UTC; Posted 19 September 2008
Posted to: Molecular Cell Biology, Bioinformatics
Bioinformatic approaches for the genetic and phenotypic characterization of a Saccharomyces cerevisiae wine yeast collection
The objective of the present study was to compare genetic and phenotypic variation of 103 Saccharomyces cerevisiae strains isolated from winemaking environments. We used bioinformatics approaches t…
Received 11 September 2008 08:12 UTC; Posted 11 September 2008
Posted to: Bioinformatics
Analysis of Genetic Interaction Maps Reveals Functional Pleiotropy
Epistatic or genetic interactions, representing the effects of mutations on the phenotypes caused by other mutations, can be very helpful for uncovering functional relationships between genes. Rece…
Received 13 August 2008 21:22 UTC; Posted 14 August 2008
Posted to: Bioinformatics
Yeast surface 2-hybrid to detect protein-protein interactions via the secretory pathway as a platform for antibody discovery
High throughput methods to measure protein-protein interactions will facilitate uncovering pairs of unknown interactions as well as designing new interactions. We have developed a platform to detec…
Received 10 July 2008 20:57 UTC; Posted 11 July 2008
Posted to: Biotechnology
Population genomics of domestic and wild yeasts
The natural genetics of an organism is determined by the distribution of sequences of its genome. Here we present one- to four-fold, with some deeper, coverage of the genome sequences of over seven…
Received 19 June 2008 10:26 UTC; Posted 20 June 2008
Posted to: Ecology, Genetics & Genomics, Bioinformatics, Evolutionary Biology
A Genome-Wide Analysis Reveals Significant Overlap of Transcription and DNA Repair in Stationary Phase Yeast
The association between transcription and DNA repair is acknowledged as a player in the generation of mutations in a non-random fashion in prokaryotes and eukaryotes. Previous studies demonstrated …
Received 27 January 2008 20:07 UTC; Posted 28 January 2008
Posted to: Genetics & Genomics, Evolutionary Biology
