Submissions tagged with transcription factors
(6 documents)
Rethinking Leucine Zipper – a ubiquitous signal transduction motif
In this essay we attempt to reconsider the concept of the “Leucine Zipper” (LZ) protein oligomerization motif. Reasoning on the wealth of existing data, we suggest that despite of the structural si…
Received 22 May 2009 07:26 UTC; Posted 22 May 2009
Posted to: Cancer, Immunology, Molecular Cell Biology, Bioinformatics
Nucleosome-mediated cooperativity between transcription factors
Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes. The classical model of cooperat…
Received 16 January 2009 23:21 UTC; Posted 21 January 2009
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology, Bioinformatics
Fundamentally different strategies for transcriptional regulation are revealed by analysis of binding motifs
To regulate a particular gene, a transcription factor (TF) needs to bind a specific genome location. How is this genome address specified amid the presence of ~106-109 decoy sites? Our analysis…
Received 27 December 2008 20:53 UTC; Posted 28 December 2008
Posted to: Genetics & Genomics, Molecular Cell Biology, Bioinformatics, Evolutionary Biology
Discovery of transcription factor binding sites through integration of generic motif finders
Locating transcription factor binding sites is a key step in understanding gene regulation. Due to its importance, many de novo motif-finding methods have been proposed. Individually, these motif…
Received 25 October 2007 09:49 UTC; Posted 25 October 2007
Posted to: Biotechnology, Bioinformatics
PlnTFDB: Plant Transcription Factor Database – Update
PlnTFDB is a publicly available computational resource comprising putative complete sets of transcription factors from plants. The original database listed the putative complete sets of TFs from fi…
Received 24 September 2007 11:25 UTC; Posted 26 September 2007
Posted to: Ecology, Bioinformatics, Plant Biology
Plant Transcription Factors @ uni-potsdam.de
We present the Plant Transcription Factor Database (PlnTFDB), and the putative complete set of TFs in the algae Chlamydomonas reinhardtii, Ostreococcus tauri and the vascular plants _Oryza sati…
Received 26 June 2007 12:09 UTC; Posted 26 June 2007
Posted to: Ecology, Bioinformatics, Plant Biology
