Submissions tagged with tolerance
(2 documents)
1 vote
Cyclin kinase inhibitor p21: a mediator of immune tolerance: direct and indirect evidence
Background: Uncontrolled proliferation of T-cells is considered a barrier to the induction of transplantation tolerance by T regulatory cells. Therefore, cyclin kinase inhibitor p21, one of the m…
Received 26 June 2009 19:29 UTC; Posted 29 June 2009
Posted to: Immunology
3 votes
Immunity to self co-generates regulatory T cells
Immune responses to self are kept in check by tolerance mechanisms, including suppression by regulatory T cells (Tregs). The defective generation of Tregs specific for self-antigens may lead to aut…
Received 08 April 2008 23:43 UTC; Posted 09 April 2008
Posted to: Immunology
