Submissions tagged with systems biology
(28 documents)
Systems Biology Markup Language (SBML) Level 2: Structures and Facilities for Model Definitions
With the rise of Systems Biology as a new paradigm for understanding biological processes, the development of quantitative models is no longer restricted to a small circle of theoreticians. The dra…
Received 26 October 2007 08:21 UTC; Posted 05 November 2007
Posted to: Bioinformatics
Intracellular Regulatory Networks are close to Monotone Systems
Several meso-scale biological intracellular regulatory networks that have specified directionality of interactions have been recently assembled from experimental literature. Directed networks where…
Received 23 January 2007 16:57 UTC; Posted 23 January 2007
Posted to: Molecular Cell Biology, Bioinformatics
Dynamic Topology of Biological Networks
The mammalian cell can be represented as a large modular network that consists of a central signal network that interacts with and regulates multiple cellular machines that are responsible for phen…
Received 23 January 2007 16:48 UTC; Posted 23 January 2007
Posted to: Molecular Cell Biology, Neuroscience, Pharmacology, Bioinformatics
The Systems Biology Markup Language (SBML): Where It’s Been and Where It’s Going
A cornerstone of systems biology is the use of computational modeling, by which hypotheses can be cast into a quantitative form that can be tested systematically. The use of computational modeling…
Received 22 January 2007 04:39 UTC; Posted 22 January 2007
Posted to: Biotechnology, Bioinformatics
Evolving standards and infrastructure for systems biology: SBML, SBGN, and BioModels.net
Systems biology has arisen through the convergence of theoretical, computational, and mathematical modeling of systems and the need to understand the wealth of information being rapidly generated i…
Received 22 January 2007 04:29 UTC; Posted 22 January 2007
Posted to: Biotechnology, Bioinformatics
The Systems Biology Markup Language (SBML) Level 2 Version 2
The Systems Biology Markup Language (SBML) is a machine-readable model representation language for software tools in computational systems biology. By supporting SBML as an input/output format, dif…
Received 22 January 2007 04:01 UTC; Posted 22 January 2007
Posted to: Biotechnology, Bioinformatics
Open Standards and Resources in Systems Biology: collaborative scale-up toward virtual life
The practise of Systems Biology relies on interfaces. Interfacesbetween the entities we study: the paradigm moved from a physicalobject centric view toward a relationship-centric one; interface…
Received 30 November 2006 13:26 UTC; Posted 30 November 2006
Posted to: Biotechnology
DARPP-32 is a robust integrator of dopamine and glutamate signals
Integration of neurotransmitter and neuromodulator signals in the striatum plays a central role in the functions and dysfunctions of the basal ganglia. DARPP-32 is a key actor of this integration i…
Received 30 November 2006 13:14 UTC; Posted 30 November 2006
Posted to: Neuroscience
