Submissions tagged with systems biology
(28 documents)
Visualization of the Phosphoproteomic Data from AfCS with the Google Motion Chart Gadget
Results from multivariate molecular biological experiments become increasingly complex. Hence, the challenge of projecting high-dimensional data onto few dimensions for effective data visualization…
Received 16 April 2009 15:39 UTC; Posted 16 April 2009
Posted to: Biotechnology, Molecular Cell Biology, Bioinformatics
Computational methods in cancer gene networking
In the past few years, many high-throughput techniques have been developed and applied to biological studies. These techniques such as “next generation” genome sequencing, chip-on-chip, microarray …
Received 30 December 2008 19:47 UTC; Posted 06 January 2009
Posted to: Cancer, Genetics & Genomics, Bioinformatics
Polar Mapper: a computational tool for integrated visualization of protein interaction networks and mRNA expression data
Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the und…
Received 15 December 2008 12:04 UTC; Posted 15 December 2008
Posted to: Genetics & Genomics, Bioinformatics
Local and global modes of drug action in biochemical networks
It becomes increasingly accepted that a shift is needed from the traditional target-based approach of drug development to an integrated perspective of drug action in biochemical systems. We here pr…
Received 13 November 2008 15:22 UTC; Posted 14 November 2008
Posted to: Biotechnology
Embedding machine-readable proteins interactions data in scientific articles for easy access and retrieval
Extraction of protein-protein interactions data from scientific literature remains a hard, time- and resource-consuming task. This task would be greatly simplified by embedding in the source, i.e. ...
Received 29 September 2008 14:22 UTC; Posted 01 October 2008
Posted to: Bioinformatics
Systems Biology Graphical Notation: Process Diagram Level 1
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society wou…
Received 22 September 2008 20:40 UTC; Posted 23 September 2008
Posted to: Biotechnology, Bioinformatics
A network-based signaling mechanism of cancer development and progression
We conducted a comprehensive analysis of a manually curated human signaling network containing 1634 nodes and 5089 signaling regulatory relations by integrating cancer-associated genetically and ep…
Received 27 August 2008 19:33 UTC; Posted 27 August 2008
Posted to: Cancer, Genetics & Genomics, Bioinformatics
Building Block and Building Rule: Dual Descriptor Method for Biological Sequence Analysis
The emergence of “Systems Biology” in recent years highlights the systematic viewpoint of bio-system modeling. Building on such a background, Dual Descriptor Method, a generic methodology for biolo…
Received 23 August 2008 17:57 UTC; Posted 26 August 2008
Posted to: Biotechnology, Bioinformatics
GabiPD: GABI primary database – a plant integrative ‘omics’ database
The GABI Primary Database, GabiPD, was established eight years ago in the frame of the German initiative for Genome Analysis of the Plant Biological System (Genomanalyse im biologischen System Pfla…
Received 22 August 2008 10:07 UTC; Posted 22 August 2008
Posted to: Bioinformatics, Plant Biology
Systems Pharmacology
The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008. The sl…
Received 01 April 2008 16:19 UTC; Posted 02 April 2008
Posted to: Biotechnology, Chemistry, Pharmacology, Bioinformatics
