Submissions tagged with structure
(2 documents)
Shelling the Voronoi interface of protein-protein complexes predicts residue activity and conservation
The accurate description and analysis of protein-protein interfaces remains a challenging task. Traditional definitions, based on atomic contacts or changes in solvent accessibility, tend to over- ...
Received 21 June 2008 06:54 GMT; Posted 23 June 2008
Posted to: Chemistry, Molecular Cell Biology, Bioinformatics
Steroid substrate-induced epimerase mechanism in the active site of the human 11β-hydroxysteroid dehydrogenase type 1
Cytochrome P4507B1 7α-hydroxylates dehydroepiandrosterone (DHEA), epiandrosterone (EpiA) and 5α-androstane-3β,17β-diol (Adiol). 11β-Hydroxysteroid dehydrogenase type 1 (11&...
Received 06 May 2008 15:51 GMT; Posted 06 May 2008
Posted to: Chemistry, Pharmacology