Submissions tagged with signaling
(5 documents)
Visualization of the Phosphoproteomic Data from AfCS with the Google Motion Chart Gadget
Results from multivariate molecular biological experiments become increasingly complex. Hence, the challenge of projecting high-dimensional data onto few dimensions for effective data visualization…
Received 16 April 2009 15:39 UTC; Posted 16 April 2009
Posted to: Biotechnology, Molecular Cell Biology, Bioinformatics
Specification of spatial relationships in directed graphs of cell signaling networks
Graph theory provides a useful and powerful tool for the analysis of cellular signaling networks. Intracellular components such as cytoplasmic signaling proteins, transcription factors and genes ar…
Received 03 July 2008 16:25 UTC; Posted 04 July 2008
Posted to: Molecular Cell Biology, Bioinformatics
Alignment of Linear Biochemical Pathways Using Protein Structural Classification
Metabolic, signaling and regulatory pathways form the basis of biological processes and are important for the analysis of cellular behavior and evolution. This paper presents an approach of alignin…
Received 03 June 2008 16:22 UTC; Posted 03 June 2008
Posted to: Bioinformatics
Tumor-associated EGFR over-expression specifically activates Stat3 and Smad7 resulting in desensitization of TGF-β signaling
Transforming Growth Factor-β (TGF-β) and Epidermal Growth Factor (EGF) signaling pathways are both independently implicated as key regulators in tumor formation and progression. Here, we …
Received 23 January 2008 01:47 UTC; Posted 23 January 2008
Posted to: Cancer, Molecular Cell Biology
Activation of TRF3 Transcription Factor by Small Interfering RNAs
RNA interference (RNAi) is a conserved biological response to double-stranded RNAs that results in posttranscriptional silencing of target gene expression. Double-stranded processed RNAs of 21-23 n…
Received 04 October 2007 06:58 UTC; Posted 04 October 2007
Posted to: Molecular Cell Biology
