Submissions tagged with shRNA
(3 documents)
Technical Note: The Use of RNA-interference as a Tool to Find Proteins Involved in Melanosome Formation or Transport
Melanosomes are lysosome-related organelles that produce and transport the pigment melanin within melanocytes. Mutations in proteins required for melanosome transport and formation lead to a range …
Received 10 July 2009 18:38 UTC; Posted 14 July 2009
Posted to: Molecular Cell Biology
Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model
Using an adenoviral system as a delivery mediator of therapeutic gene, we investigated the therapeutic effects of the use of combined MDR1 shRNA and human NIS (hNIS) radioiodine gene therapy in…
Received 02 June 2009 13:12 UTC; Posted 02 June 2009
Posted to: Cancer
A novel class of endogenous shRNAs in human cells
Until now it is still not clear how many types and amounts of small RNAs (sRNAs) exist in humans. Here we report the identification of 1258 distinct sRNAs derived from intronic regions of protein-c…
Received 22 January 2008 09:16 UTC; Posted 23 January 2008
Posted to: Biotechnology
