Submissions tagged with nuclear receptors
(4 documents)
Independent elaboration of steroid hormone signaling pathways in Metazoans
Steroid hormones regulate many physiological processes in vertebrates, nematodes and arthropods through binding to nuclear receptors (NR), a metazoan-specific family of ligand-activated transcripti…
Received 25 June 2009 20:55 UTC; Posted 26 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Earth & Environment, Evolutionary Biology
3D model of amphioxus steroid receptor complexed with estradiol
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chorda…
Received 03 June 2009 21:14 UTC; Posted 05 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Evolutionary Biology
Trichoplax, the simplest known animal, contains an estrogen-related receptor but no estrogen receptor: Implications for estrogen receptor evolution
Although, as their names imply, estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to each other are not fully unders…
Received 12 August 2008 02:08 UTC; Posted 13 August 2008
Posted to: Developmental Biology, Ecology, Evolutionary Biology
Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors
Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to eac…
Received 06 May 2008 21:45 UTC; Posted 06 May 2008
Posted to: Developmental Biology, Ecology, Evolutionary Biology
