Submissions tagged with mouse
(6 documents)
Developing a Mammalian Behaviour Ontology
The use of the Entity + Quality (EQ) model in phenotypic descriptions is dependent on the use of specialised domain ontologies to define the entity under observation. A domain currently lacking a …
Received 06 August 2009 13:43 UTC; Posted 07 August 2009
Posted to: Bioinformatics
Standard operating procedures (SOP) in experimental stroke research: SOP for middle cerebral artery occlusion in the mouse
Recently, systematic reviews have found quantitative evidence that low study quality may have introduced a bias into preclinical stroke research. Monitoring, auditing, and standard operating proced…
Received 28 July 2009 16:54 UTC; Posted 28 July 2009
Posted to: Neuroscience
GUDMAP – An Online GenitoUrinary Resource
The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is a consortium of laboratories working to provide the scientific and medical community with gene expression data and tools to facil…
Received 29 May 2009 13:53 UTC; Posted 30 May 2009
Posted to: Developmental Biology, Genetics & Genomics, Bioinformatics
IMGT/GENE-DB: genomic reference sequences for human and mouse IG and TR genes and alleles
The immunoglobulin (IG) and T cell receptor (TR) major loci span about 6 Megabases (Mb) of the human genome on chromosomes 2, 7, 14 and 22, and 9 Mb in mouse on chromosomes 6, 12, 13, 14 and 16. Th…
Received 23 April 2009 13:26 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Immunology, Bioinformatics
Introduction of Transmembrane Inner Ear (tmie) Gene Can Recover the Hearing Impairment and Abnormal Behavior in the Circling Mouse
The spontaneous mutant circling mouse (cir/cir) shows a circling behavior and hearing loss. We produced transgenic mice overexpressing the causative gene, transmembrane inner ear (tmie), for the ph…
Received 22 July 2008 07:13 UTC; Posted 28 July 2008
Posted to: Developmental Biology, Genetics & Genomics, Neuroscience
Intra- and inter-individual genetic differences in gene expression
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components…
Received 15 April 2008 01:17 UTC; Posted 15 April 2008
Posted to: Genetics & Genomics, Bioinformatics