Submissions tagged with motifs
(4 documents)
The Eukaryotic Linear Motif Resource (ELM): Regulatory Sites in Proteins
Linear motifs are short and evolutionarily variable sequence patterns associated with particular functions often involving post-translational modifications, such as phosphorylation, acetylation, gl…
Received 23 April 2009 10:26 UTC; Posted 23 April 2009
Posted to: Bioinformatics
Fundamentally different strategies for transcriptional regulation are revealed by analysis of binding motifs
To regulate a particular gene, a transcription factor (TF) needs to bind a specific genome location. How is this genome address specified amid the presence of ~106-109 decoy sites? Our analysis…
Received 27 December 2008 20:53 UTC; Posted 28 December 2008
Posted to: Genetics & Genomics, Molecular Cell Biology, Bioinformatics, Evolutionary Biology
MEMOFinder: combining de novo motif prediction methods with a database of known motifs
Background: Methods for finding overrepresented sequence motifs are useful in several key areas of computational biology. They aim at detecting very weak signals responsible for biological proces…
Received 17 December 2008 13:40 UTC; Posted 22 December 2008
Posted to: Bioinformatics
Data mining of protein families using common peptides
Predicting the function of a protein from its sequence is typically addressed using sequence-similarity. Here we propose a motif-based approach, using supervised motif extraction from protein seque…
Received 14 August 2008 08:55 UTC; Posted 14 August 2008
Posted to: Bioinformatics
