Submissions tagged with modeling
(4 documents)
Systems Biology Graphical Notation: Process Diagram Level 1
Standard graphical representations have played a crucial role in science and engineering throughout the last century. Without electrical symbolism, it is very likely that our industrial society wou...
Received 22 September 2008 20:24 GMT; Posted 23 September 2008
Posted to: Biotechnology, Bioinformatics
A three-dimensional stochastic spatio-temporal model of cell spreading
Cell motility is important for many physiological processes and the underlyingbiochemical reactions motility have been well characterized. Mathematical models, usingthe biochemical reactions and fo...
Received 03 December 2007 15:08 GMT; Posted 03 December 2007
Posted to: Biotechnology, Molecular Cell Biology, Bioinformatics
Evolution of malaria virulence in cross-generation transmission through selective immune pressure
Theoretical arguments and some mathematical models of host-parasite coevolution (e.g. [1- 6]) suggest host immunity as the driving source for the evolution of parasite virulence. Imperfect vaccines...
Received 23 June 2007 19:32 GMT; Posted 25 June 2007
Posted to: Evolutionary Biology and Ecology, Immunology, Bioinformatics
Molecular Static and Dynamic Analyses reveal Flaw in Murine Model used by US FDA to Detect Drug Carcinogenicity
The US FDA currently accepts carcinogenicity studies of pharmaceutical drugs based on murine models. In addition to 6 month studies with p53(+/-) and ras.H2 transgenic mice, lifetime studies (typic...
Received 15 June 2007 18:05 GMT; Posted 15 June 2007
Posted to: Biotechnology, Cancer, Immunology, Pharmacology, Bioinformatics