http://precedings.nature.com/tags/microbiology Recently posted documents tagged with 'microbiology' Nature Publishing Group en Nature Precedings http://precedings.nature.com/images/header_logo.gif http://precedings.nature.com http://precedings.nature.com/documents/2985/version/1 Streptococcus equi subspecies equi (S. equi) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, more commonly known as Strangles. The disease is highly prevalent, can be severe and spread easily by visibly infected animals or by carrier animals that show no clinical signs of disease. Antibiotic treatment is usually ineffective. However, the majority of horses develop immunity to re-infection, suggesting that vaccination should be a feasible way to prevent the infection. Live attenuated vaccine strains of S. equi are available but adverse reactions have been reported and they suffer from a short duration of immunity. Thus, a safe and effective vaccine against S. equi is highly desirable. In this report, Welsh mountain ponies vaccinated with a combination of seven recombinant S. equi proteins, were significantly protected from experimental infection by S. equi, resembling the spontaneous disease. The protective antigens consisted of five surface localized proteins and two IgG endopeptidases. The results from a second vaccination trial indicate that the endopeptidases were important for good protection. The similarity of S. equi to other pyogenic streptococci suggests that our findings have broader implications for the prevention of streptococcal infections. http://precedings.nature.com/documents/2985/version/1 Thu, 26 Mar 2009 17:23:17 UTC Protective vaccination in the horse against Streptococcus equi with recombinant antigens hdl:10101/npre.2009.2985.1 2009-03-26 Jan-Ingmar Flock Nature Precedings 2009-03-26T17:23:17Z Manuscript Immunology Microbiology http://creativecommons.org/licenses/by/3.0/ http://precedings.nature.com/documents/1875/version/1 Mosquito causes problems in both disease transmission and disturbance to people’s daily life. The controlling methods used now are mainly application of chemical pesticides which result in serious harm to environment. Biological control of the pest is one of the ideal ways. But, lack of suitable agent makes it difficult to extend this technique in wider scope. Pythium guiyangense Su is a newly found fungal pathogen of mosquitoes and is promising for practical use. Here we summarize a list of mosquitoes that can be infected by the fungus so far, which shows the potential significance of the application of the fungus in the future. http://precedings.nature.com/documents/1875/version/1 Mon, 12 May 2008 13:44:31 UTC A Report of the Mosquito Host Range of Pythium guiyangense Su hdl:10101/npre.2008.1875.1 2008-05-12 Xiaoqing Su Nature Precedings 2008-05-12T13:44:31Z Manuscript Microbiology Earth & Environment http://creativecommons.org/licenses/by/3.0/