Submissions tagged with genetic variation
(3 documents)
Population genomics of domestic and wild yeasts
The natural genetics of an organism is determined by the distribution of sequences of its genome. Here we present one- to four-fold, with some deeper, coverage of the genome sequences of over seven...
Received 19 June 2008 09:14 GMT; Posted 20 June 2008
Posted to: Evolutionary Biology and Ecology, Genetics, Microbiology, Bioinformatics
Intra- and inter-individual genetic differences in gene expression
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components...
Received 14 April 2008 23:30 GMT; Posted 15 April 2008
Posted to: Genetics, Bioinformatics
Estimation of DNA Sequence Context-dependent Mutation Rates Using Primate Genomic Sequences: Application to Estimation of Selection Bias in Protein (Human TP53) Evolution
Understanding of the mechanism of DNA mutation process is critical for studying the functional consequences of genetic variation in clinical medicine (eg. drug response) as well as other complex tr...
Received 19 October 2007 18:28 GMT; Posted 23 October 2007
Posted to: Evolutionary Biology and Ecology, Bioinformatics