Submissions tagged with gene ontology
(21 documents)
Development of an Ontology of Microbial Phenotypes (OMP)
AbstractPhenotypic data are routinely used to elucidate gene and protein function in most organisms amenable to experimental manipulation. However, although phenotype ontologies exist for many …
Received 17 August 2009 22:31 UTC; Posted 19 August 2009
Posted to: Microbiology, Bioinformatics
Using Ontology Fingerprints to evaluate genome-wide association study results
We describe an approach to characterize genes or phenotypes via ontology fingerprints which are composed of Gene Ontology (GO) terms overrepresented among those PubMed abstracts linked to the genes…
Received 14 August 2009 20:36 UTC; Posted 14 August 2009
Posted to: Genetics & Genomics, Bioinformatics
Using the Gene Ontology to Annotate Biomedical Journal Articles
We are creating a gold-standard corpus of manually annotated full-text biomedical journal articles toward natural-language-processing applications. Central to this is our use of entire ontologies …
Received 05 August 2009 22:44 UTC; Posted 06 August 2009
Posted to: Bioinformatics
A Bayesian Hierarchical Model to Derive Novel Gene Networks from Gene Ontology Fingerprints
We developed a Bayesian hierarchical model to identify gene networks based on the similarity score generated from comparing the gene ontology fingerprints of gene pairs. Genes in this network were …
Received 29 July 2009 15:15 UTC; Posted 29 July 2009
Posted to: Bioinformatics
Using Ontology Fingerprints to Evaluate Genome-wide Association Results
We describe an approach to characterize genes or phenotypes via ontology fingerprints which are composed of Gene Ontology (GO) terms overrepresented among those PubMed abstracts linked to the genes…
Received 29 July 2009 15:37 UTC; Posted 29 July 2009
Posted to: Genetics & Genomics, Bioinformatics
Cross-Product Extensions of the Gene Ontology
The Gene Ontology is being normalized and extended to include computable logical definitions. These definitions are partitioned into mutually exclusive cross-product sets, many of which reference o…
Received 28 July 2009 21:38 UTC; Posted 29 July 2009
Posted to: Genetics & Genomics, Bioinformatics
Integrating Text Mining into the MGI Biocuration Workflow
A major challenge for the development of resources for functional and comparative genomics is the extraction of data from the biomedical literature. Although text retrieval and extraction for biol…
Received 20 May 2009 11:36 UTC; Posted 20 May 2009
Posted to: Bioinformatics
Standardization in UniProtKB/Swiss-Prot
Within the UniProt consortium, the UniProtKB/Swiss-Prot knowledge base provides the international community with a stable, comprehensive, fully classified, richly and accurately annotated protein s…
Received 04 May 2009 09:41 UTC; Posted 08 May 2009
Posted to: Bioinformatics
GOAssay: from Gene Ontology to Assays IDentifiers – Towards Automatic Functional Annotation of PubChem BioAssays
OBJECTIVES: We report on a experiment to functionally annotate PubChem assays using the Gene Ontology Categorizer (GOCat). METHODS and MATERIALS: The assays are processed to filter out non func…
Received 24 April 2009 20:48 UTC; Posted 28 April 2009
Posted to: Chemistry, Genetics & Genomics, Bioinformatics
Grid technology for collaborative ontology development
In contrast with the centrally-organised curation of the Gene Ontology, many biological ontologies are developed by loosely-organised groups who develop their ontology remotely. These groups tend t…
Received 27 April 2009 19:36 UTC; Posted 27 April 2009
Posted to: Bioinformatics
