Submissions tagged with gene expression
(31 documents)
Limusaurus and bird digit identity
Limusaurus is a remarkable herbivorous ceratosaur unique among theropods in having digits II, III and IV, with only a small metacarpal vestige of digit I. This raises interesting questions regard…
Received 06 October 2009 03:05 UTC; Posted 06 October 2009
Posted to: Developmental Biology, Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
Gender differences in a Drosophila transcriptomic model of chronic pentylenetetrazole induced behavioral deficit
A male Drosophila model of locomotor deficit induced by chronic pentylenetetrazole (PTZ), a proconvulsant used to model epileptogenesis in rodents, has recently been described. Antiepileptic drugs …
Received 25 July 2009 08:04 UTC; Posted 27 July 2009
Posted to: Genetics & Genomics, Neuroscience, Pharmacology, Bioinformatics
A Drosophila systems model of withdrawal from chronic pentylenetetrazole relevant in post-epileptogenesis
Rodent kindling induced by pentylenetetrazole (PTZ) is an established model of epileptogenesis and antiepileptic drug (AED) testing. Recently, a Drosophila systems model has been described in which…
Received 21 July 2009 16:19 UTC; Posted 21 July 2009
Posted to: Genetics & Genomics, Neuroscience, Pharmacology, Bioinformatics
A novel Drosophila transcriptomic and behavioral model detects potassium chloride with therapeutic potential
In a newly described Drosophila model, two of the five antiepileptic drugs (AEDs) tested, sodium valproate (NaVP) and levetiracetam (LEV), not ethosuximide (ETH), gabapentin (GBP) and vigabatrin …
Received 14 July 2009 15:23 UTC; Posted 17 July 2009
Posted to: Genetics & Genomics, Neuroscience, Pharmacology, Bioinformatics
Transcriptomic analysis implicates ribosomal and energy metabolic pathways in antiepileptic drug action in a Drosophila model
Mechanisms of long term action of antiepileptic drugs (AEDs), used in treating epilepsy and many other neurological and psychiatric disorders, are poorly understood. Recently, a novel Drosophila tr…
Received 03 July 2009 14:57 UTC; Posted 07 July 2009
Posted to: Genetics & Genomics, Neuroscience, Pharmacology, Bioinformatics
Systems level analysis of transgenerational spermatogenic inheritance predicts biomarkers and underlying pathways
Transgenerational spermatogenic inheritance of adult male acquired CNS gene expression characteristics has recently been discovered using a Drosophila systems model. In this novel mode of inheritan…
Received 03 June 2009 14:08 UTC; Posted 05 June 2009
Posted to: Genetics & Genomics
GUDMAP – An Online GenitoUrinary Resource
The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is a consortium of laboratories working to provide the scientific and medical community with gene expression data and tools to facil…
Received 29 May 2009 13:53 UTC; Posted 30 May 2009
Posted to: Developmental Biology, Genetics & Genomics, Bioinformatics
A novel superior factor widely controlling the rice grain quality
Synthesis of storage starch and protein accumulation is the main action of endosperm organogenesis in term of the economic importance of rice. This event is strongly disturbed by abiotic stresses s…
Received 25 May 2009 07:42 UTC; Posted 26 May 2009
Posted to: Plant Biology
Literature Triage and Indexing in the Mouse Genome Informatics (MGI) Group
The Mouse Genome Informatics (MGI; http://www.informatics.jax.org) group is comprised of several collaborating projects including the Mouse Genome Database (MGD) Pr…
Received 13 May 2009 16:01 UTC; Posted 14 May 2009
Posted to: Cancer, Developmental Biology, Genetics & Genomics, Immunology, Molecular Cell Biology, Neuroscience, Bioinformatics
Significance tests for comparing digital gene expression profiles
Most of the statistical tests currently used to detect differentially expressed genes are based on asymptotic results, and perform poorly for low expression tags. Another problem is the common us…
Received 28 August 2008 14:08 UTC; Posted 29 August 2008
Posted to: Genetics & Genomics, Bioinformatics
