Submissions tagged with estrogen receptor evolution
(3 documents)
3D model of amphioxus steroid receptor complexed with estradiol
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chorda…
Received 03 June 2009 21:14 UTC; Posted 05 June 2009
Posted to: Cancer, Developmental Biology, Bioinformatics, Evolutionary Biology
3D model of lamprey estrogen receptor with estradiol and 15α-hydroxy-estradiol
Lamprey, a basal vertebrate, contains orthologs of the estrogen receptor (ER), progesterone receptor and corticoid receptor. A perplexing property of lamprey is that 15α-hydroxy-steroids are…
Received 09 January 2009 02:16 UTC; Posted 09 January 2009
Posted to: Developmental Biology, Ecology, Earth & Environment
Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors
Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to eac…
Received 06 May 2008 21:45 UTC; Posted 06 May 2008
Posted to: Developmental Biology, Ecology, Evolutionary Biology