Submissions tagged with drug delivery
(6 documents)
Paclitaxel delivery by micro/nano encapsulation using layer-by-layer assembly
A novel formulation of paclitaxel (PTX) has been developed by providing multilayer assembly over drug loaded porous CaCO3 microparticles (CaCO3 MP) using combination of biocompatible and biodegrada…
Received 21 January 2009 11:51 UTC; Posted 22 January 2009
Posted to: Pharmacology
Genome-wide transcription analysis of interaction between the human macrophage and Mycobacterium tuberculosis during concurrent drug administration by conventional and novel methods
Targeted drug delivery to alveolar macrophages harboring Mycobacterium tuberculosis (Mtb) holds promise of high efficacy against pulmonary tuberculosis (TB). It was investigated whether inhalable m…
Received 31 October 2008 05:43 UTC; Posted 04 November 2008
Posted to: Pharmacology
PLA Microparticles for Pulmonary Delivery of AntiTB drugs: Biodistribution study
A dry powder inhalable (DPI) microparticles comprising anti-tuberculosis drugs incorporated in biodegradable polymers was developed for the treatment of pulmonary tuberculosis (P. Muttil et al. 2…
Received 29 October 2008 05:46 UTC; Posted 29 October 2008
Posted to: Pharmacology
A Targeted Therapeutic Rescues Botulinum Toxin-A Poisoned Neurons
Botulinum neurotoxin (BoNT), a Category A biothreat agent, is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses. BoNT acts specifically by bloc…
Received 01 August 2008 17:21 UTC; Posted 13 August 2008
Posted to: Biotechnology, Molecular Cell Biology, Neuroscience
Successful use of axonal transport for drug delivery by synthetic molecular vehicles
We report the use of axonal transport to achieve intraneural drug delivery. We constructed a novel tripartite complex of an axonal transport facilitator conjugated to a linker molecule bearing up t…
Received 06 August 2008 15:14 UTC; Posted 07 August 2008
Posted to: Biotechnology, Chemistry, Molecular Cell Biology, Neuroscience, Pharmacology
An intelligent liposome that may deliver drug molecules in a well controlled fashion
The passage of molecules, especially large ones, through the cellular membrane is a very important problem for some biotechnological applications, such as drug delivery. The appearance of pores in …
Received 11 October 2007 08:34 UTC; Posted 12 October 2007
Posted to: Biotechnology
