Submissions tagged with database
(39 documents)
The Eukaryotic Linear Motif Resource (ELM): Regulatory Sites in Proteins
Linear motifs are short and evolutionarily variable sequence patterns associated with particular functions often involving post-translational modifications, such as phosphorylation, acetylation, gl…
Received 23 April 2009 10:26 UTC; Posted 23 April 2009
Posted to: Bioinformatics
Worm Annotation in the UniProt Knowledgebase (UniProtKB)
The nematode worm, Caenorhabditis elegans, was the first multicellular organism to be sequenced. Its genome was published in 1998, providing an impetus for gene and protein annotation. Recently, ...
Received 23 April 2009 11:47 UTC; Posted 23 April 2009
Posted to: Bioinformatics
Xenopus and Zebrafish Annotation in the UniProt Knowledgebase (UniProtKB)
The African clawed frog Xenopus laevis and the zebrafish Danio rerio have both proved to be good model organisms for studying early vertebrate cellular and developmental biology. More recently, the…
Received 23 April 2009 10:30 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
IMGT/Automat: the strategy for the annotation of human and mouse cDNA nucleotide sequences of IG and TR
The cDNA sequences of immunoglobulins (IG) and T cell receptors (TR) represent more than one half of the sequences in the IMGT® nucleotide database IMGT/LIGM-DB1 and 75% of them are from human …
Received 23 April 2009 13:49 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Immunology, Bioinformatics
Developing a Text Mining Prototype for the Comparative Toxicogenomics Database Biocuration Process
Understanding interactions between environmental chemicals and genes provides insights into the mechanisms of chemical action, disease susceptibility, therapeutic drug interactions, and toxicity. T…
Received 22 April 2009 16:07 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Pharmacology, Bioinformatics
Data submission and curation for caArray, a standard based microarray data repository system
caArray is an open-source, open development, web and programmatically accessible array data management system developed at National Cancer Institute. It was developed to support the exchange of arr…
Received 22 April 2009 14:16 UTC; Posted 22 April 2009
Posted to: Cancer, Bioinformatics
Beyond Structure: KiSAO and TEDDY—Two Ontologies Addressing Pragmatical and Dynamical Aspects of Computational Models in Systems Biology
Computational models are becoming more and more the central scientific paradigm for understanding the complexity of living systems. With the increasing number and size of these models there is a gr…
Received 22 April 2009 13:57 UTC; Posted 22 April 2009
Posted to: Molecular Cell Biology, Bioinformatics
The SOL Genomics Network Model: Making Community Annotation Work
The concept of community annotation is a growing discipline for achieving participation of the research community in depositing up‐to‐date knowledge in biological databases.The Solanaceae Genomic…
Received 22 April 2009 13:21 UTC; Posted 22 April 2009
Posted to: Bioinformatics, Plant Biology
Terminizer – Assisting Mark-Up of Text Using Ontological Terms
We present a tool that automatically detects ontological terms in free text. Once candidate terms have been identified the results are displayed either overlaid on the original text or in a list or…
Received 22 April 2009 11:53 UTC; Posted 22 April 2009
Posted to: Bioinformatics
Ontology-based Assisted Curation of Biomedical Data
Manual curation of biomedical data is highly accurate but time consuming, and does not scale with the ever increasing growth of biomedical literature. Text mining as a high-throughput computational…
Received 22 April 2009 10:34 UTC; Posted 22 April 2009
Posted to: Bioinformatics
