Submissions tagged with curation
(30 documents)
Xenopus and Zebrafish Annotation in the UniProt Knowledgebase (UniProtKB)
The African clawed frog Xenopus laevis and the zebrafish Danio rerio have both proved to be good model organisms for studying early vertebrate cellular and developmental biology. More recently, the…
Received 23 April 2009 10:30 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Community Outreach through Genomics Education Partnership
The J Craig Venter Institute (JCVI) has recently partnered with undergraduate university faculty to expand the scope of education and outreach program as part of the NIAID’s BRC initiative, by join…
Received 22 April 2009 20:10 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Microbiology, Bioinformatics
Developing a Text Mining Prototype for the Comparative Toxicogenomics Database Biocuration Process
Understanding interactions between environmental chemicals and genes provides insights into the mechanisms of chemical action, disease susceptibility, therapeutic drug interactions, and toxicity. T…
Received 22 April 2009 16:07 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Pharmacology, Bioinformatics
The SOL Genomics Network Model: Making Community Annotation Work
The concept of community annotation is a growing discipline for achieving participation of the research community in depositing up‐to‐date knowledge in biological databases.The Solanaceae Genomic…
Received 22 April 2009 13:21 UTC; Posted 22 April 2009
Posted to: Bioinformatics, Plant Biology
Terminizer – Assisting Mark-Up of Text Using Ontological Terms
We present a tool that automatically detects ontological terms in free text. Once candidate terms have been identified the results are displayed either overlaid on the original text or in a list or…
Received 22 April 2009 11:53 UTC; Posted 22 April 2009
Posted to: Bioinformatics
P-POD, The Princeton Protein Orthology Database, as a Tool for Identifying Gene Function
P-POD, the Princeton Protein Orthology Database, classifies proteins from model organisms and medically-important organisms into families of homologs and provides curated evidence from the literatu…
Received 21 April 2009 15:24 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
An Ontology To Represent Knowledge On Animal Testing Alternatives
EU Directive 86/609/EEC for the protection of laboratory animals obliges scientists to consider whether a planned animal experiment can be replaced, reduced or refined (3Rs principle). To meet this…
Received 22 April 2009 19:48 UTC; Posted 22 April 2009
Posted to: Bioinformatics
Evidence attribution in the UniProt Knowledgebase
UniProtKB provides the scientific community with a comprehensive collection of protein sequence records containing extensive curated information including functional and sequence annotation. This i…
Received 22 April 2009 11:57 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Community curation on WikiPathways: How we assist knowledge collection
Biologists typically use knowledge represented as pathways to better understand the results of genomics experiments. Through integration of data from different omics techniques with what we already…
Received 21 April 2009 12:26 UTC; Posted 21 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Reactome – a knowledgebase of human biological pathways
Pathway curation is a powerful tool for systematically associating gene products with functions. Reactome (www.reactome.org) is a manually curated human pathway knowledgebase describing a wide rang…
Received 30 October 2007 20:56 UTC; Posted 31 October 2007
Posted to: Molecular Cell Biology, Bioinformatics