Submissions tagged with cell signalling
(2 documents)
Rethinking Leucine Zipper – a ubiquitous signal transduction motif
In this essay we attempt to reconsider the concept of the “Leucine Zipper” (LZ) protein oligomerization motif. Reasoning on the wealth of existing data, we suggest that despite of the structural si…
Received 22 May 2009 07:26 UTC; Posted 22 May 2009
Posted to: Cancer, Immunology, Molecular Cell Biology, Bioinformatics
Kinase independent inhibition of NFκB transcriptional activity by GRK5 through IκBα stabilization.
Members of the G protein receptor kinase (GRK) family that regulates receptor desensitization and members of the nuclear transcription factors family NFκB have been recently and convincingly …
Received 29 September 2007 07:20 UTC; Posted 01 October 2007
Posted to: Immunology, Molecular Cell Biology