Submissions tagged with cancer
(19 documents)
Quantitative MRI and MR Spectroscopy of Multiple Sclerosis, Alzheimer’s Disease, Epilepsy and Cancer Microimaging Techniques
Clinical MRI and MRS have promise in molecular imaging. Microimaging techniques offer a promising research tool to get noninvasive data in monitoring the effect of drugs.
Received 01 August 2009 17:17 UTC; Posted 03 August 2009
Posted to: Biotechnology, Cancer, Neuroscience
NPO: Ontology for Cancer Nanotechnology Research
We present the design and development of NanoParticle Ontology (NPO). The ontology is implemented in the Ontology Web Language (OWL). The domain terms in NPO currently represent entities, which de…
Received 29 July 2009 16:13 UTC; Posted 29 July 2009
Posted to: Cancer, Bioinformatics
NPO: Ontology for Cancer Nanotechnology Research
We present the design and development of NanoParticle Ontology (NPO). The ontology is implemented in the Ontology Web Language (OWL). The domain terms in NPO currently represent entities, which de…
Received 29 July 2009 16:08 UTC; Posted 29 July 2009
Posted to: Cancer, Bioinformatics
Far-infrared rays control prostate cancer cells in vitro and in vivo
We introduce a new effective method to control hormone refractory prostate cancer cells by using an activated rubber/resin form (RB), far-infrared ray emitter, with or without sodium butyrate (SB)....
Received 20 March 2009 07:15 UTC; Posted 20 March 2009
Posted to: Cancer
A new mathematical model for radiation cell killing mechanism: Target cumulating model
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly. The more adva…
Received 18 February 2009 11:40 UTC; Posted 18 February 2009
Posted to: Cancer
Structure-based design of novel pyrazoles as aurora kinase A inhibitors.
Inhibition of Aurora kinase, a member of serine/threonine kinase involved in the regulation of cell division is emerging as a new molecular targeted cancer treatment option. Three isoforms of Auror…
Received 10 January 2009 02:52 UTC; Posted 12 January 2009
Posted to: Biotechnology, Cancer, Chemistry
Computational methods in cancer gene networking
In the past few years, many high-throughput techniques have been developed and applied to biological studies. These techniques such as “next generation” genome sequencing, chip-on-chip, microarray …
Received 30 December 2008 19:47 UTC; Posted 06 January 2009
Posted to: Cancer, Genetics & Genomics, Bioinformatics
The monoclonal antibody nBT062 conjugated to maytansinoids has potent and selective cytotoxicity against CD138 positive multiple myeloma cells in vitro and in vivo
CD138 (Syndecan1) is highly expressed on multiple myeloma (MM) cells. In this study, we examined the anti-MM effect of murine/human chimeric CD138-specific monoclonal antibody (mAb) nBT062 conjugat…
Received 07 October 2008 22:33 UTC; Posted 08 October 2008
Posted to: Cancer, Molecular Cell Biology
Off-target response to decoy oligodeoxynucleotide treatment
Background: The transcription factor PAX2 regulates key developmental processes, including mediation of resistance to apoptosis. Inappropriate PAX2 expression has been implicated in facilitating …
Received 10 September 2008 04:24 UTC; Posted 10 September 2008
Posted to: Cancer, Developmental Biology, Molecular Cell Biology
Multifunctional Nanoparticles for Imaging Guided Interventions
We describe multifunctional magnetic nanoparticles (MNPs) encapsulated in thermosensitive, drug-bearing shells and delivered to the tumor site by genetically modified and non-pathogenic strains of …
Received 14 August 2008 12:03 UTC; Posted 21 August 2008
Posted to: Biotechnology, Cancer
