Submissions tagged with bioinformatics
(39 documents)
Data submission and curation for caArray, a standard based microarray data repository system
caArray is an open-source, open development, web and programmatically accessible array data management system developed at National Cancer Institute. It was developed to support the exchange of arr…
Received 22 April 2009 14:16 UTC; Posted 22 April 2009
Posted to: Cancer, Bioinformatics
The SOL Genomics Network Model: Making Community Annotation Work
The concept of community annotation is a growing discipline for achieving participation of the research community in depositing up‐to‐date knowledge in biological databases.The Solanaceae Genomic…
Received 22 April 2009 13:21 UTC; Posted 22 April 2009
Posted to: Bioinformatics, Plant Biology
Capturing Protein Sequence Data: UniProt Knowledgebase (UniProtKB) submissions and Journal Scanning
Most sequences in UniprotKB are derived from the translation of nucleotide sequence, but we also add sequences obtained through direct sequencing of peptides by Edman degradation and tandem mass sp…
Received 21 April 2009 16:47 UTC; Posted 22 April 2009
Posted to: Molecular Cell Biology, Bioinformatics
Community curation on WikiPathways: How we assist knowledge collection
Biologists typically use knowledge represented as pathways to better understand the results of genomics experiments. Through integration of data from different omics techniques with what we already…
Received 21 April 2009 12:26 UTC; Posted 21 April 2009
Posted to: Genetics & Genomics, Bioinformatics
The future of annotation/biocuration
Talk given at 3rd International Biocuration Conference. Berlin 2009
Received 20 April 2009 07:48 UTC; Posted 21 April 2009
Posted to: Bioinformatics
Inverse relationship between genetic diversity and epigenetic complexity
Early studies of molecular evolution revealed a correlation between genetic distance and time of species divergence. This observation provoked the molecular clock hypothesis and in turn the ‘Neutr…
Received 13 January 2009 19:33 UTC; Posted 15 January 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
GabiPD: The GABI Primary Database – a plant integrative ‘omics’ database
The GABI Primary Database, GabiPD (http://www.gabipd.org/), was established in the frame of the German initiative for Genome Analysis of the Plant Biological System (GABI). The goal of GabiPD is to…
Received 20 August 2008 11:31 UTC; Posted 22 August 2008
Posted to: Genetics & Genomics, Molecular Cell Biology, Bioinformatics
Identifying Data Sharing in Biomedical Literature
Many policies and projects now encourage investigators to share their raw research data with other scientists. Unfortunately, it is difficult to measure the effectiveness of these initiatives becau…
Received 04 August 2008 19:09 UTC; Posted 04 August 2008
Posted to: Bioinformatics
An ancient adaptive episode of convergent molecular evolution confounds phylogenetic inference
Convergence can mislead phylogenetic inference by mimicking shared ancestry, but has been detected only rarely in molecular evolution. Here, we show that significant convergence occurred in snake a…
Received 26 July 2008 17:15 UTC; Posted 28 July 2008
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
The Mass-Action-Law Based GPS Concept for Bio-Informatics
The unified theory of dose and effect, as indicated by the median-effect equation for single and multiple entities and for the first and higher order kinetic/dynamic, has been established by T.C. C…
Received 18 July 2008 15:47 UTC; Posted 22 July 2008
Posted to: Biotechnology, Pharmacology, Bioinformatics
