Submissions tagged with bioinformatics
(14 documents)
GabiPD: The GABI Primary Database – a plant integrative ‘omics’ database
The GABI Primary Database, GabiPD (http://www.gabipd.org/), was established in the frame of the German initiative for Genome Analysis of the Plant Biological System (GABI). The goal of GabiPD is to...
Received 20 August 2008 11:20 GMT; Posted 22 August 2008
Posted to: Genetics, Molecular Cell Biology, Bioinformatics
Identifying Data Sharing in Biomedical Literature
Many policies and projects now encourage investigators to share their raw research data with other scientists. Unfortunately, it is difficult to measure the effectiveness of these initiatives becau...
Received 04 August 2008 18:59 GMT; Posted 04 August 2008
Posted to: Bioinformatics
An ancient adaptive episode of convergent molecular evolution confounds phylogenetic inference
Convergence can mislead phylogenetic inference by mimicking shared ancestry, but has been detected only rarely in molecular evolution. Here, we show that significant convergence occurred in snake a...
Received 26 July 2008 17:06 GMT; Posted 28 July 2008
Posted to: Evolution and Ecology, Genetics, Bioinformatics
The Mass-Action-Law Based GPS Concept for Bio-Informatics
The unified theory of dose and effect, as indicated by the median-effect equation for single and multiple entities and for the first and higher order kinetic/dynamic, has been established by T.C. C...
Received 18 July 2008 15:36 GMT; Posted 22 July 2008
Posted to: Biotechnology, Pharmacology, Bioinformatics
Check Your Data Freedom: A Taxonomy to Assess Life Science Database Openness
Molecular biology data are subject to terms of use that vary widely between databases and curating institutions. This research presents a taxonomy of contractual and technical restrictions applicab...
Received 14 July 2008 21:24 GMT; Posted 18 July 2008
Posted to: Molecular Cell Biology, Bioinformatics
Ecoinformatics: where are we, where do we want to go, and how to reach there.
Compared to other natural sciences ecological sciences has always been about seeing the bigger picture. The realization that local actions can have global impact has been the hallmark of ecological...
Received 26 June 2008 08:05 GMT; Posted 26 June 2008
Posted to: Evolution and Ecology, Bioinformatics, Earth and Environment
Function, Role, and Disposition in Basic Formal Ontology
Numerous research groups are now utilizing Basic Formal Ontology (BFO) as an upper-level framework to assist in the organization and integration of biomedical information. This paper provides eluci...
Received 02 June 2008 15:18 GMT; Posted 03 June 2008
Posted to: Bioinformatics
Inverse relationship between genetic diversity and epigenetic complexity
Early studies of molecular evolution revealed a correlation between genetic distance and time of species divergence. This observation provoked the molecular clock hypothesis and in turn the ‘Neutr...
Received 01 April 2008 23:42 GMT; Posted 02 April 2008
Posted to: Evolution and Ecology, Genetics, Bioinformatics
A review of journal policies for sharing research data
Background: Sharing data is a tenet of science, yet commonplace in only a few subdisciplines. Recognizing that a data sharing culture is unlikely to be achieved without policy guidance, some fund...
Received 20 March 2008 16:05 GMT; Posted 20 March 2008
Posted to: Bioinformatics
Prevalence and Patterns of Microarray Data Sharing
Sharing research data is a cornerstone of science. Although many tools and policies exist to encourage data sharing, the prevalence with which datasets are shared is not well understood. We report ...
Received 20 March 2008 16:21 GMT; Posted 20 March 2008
Posted to: Bioinformatics