Submissions tagged with apoptosis
(10 documents)
MicroDNAs and Transcriptional Regulation
Synthetic "microDNAs (MIDs)"is a new class of ~ 20-25 nucleotide-long DNAs capable of repressing the activity of the target gene at the level of transcription by mechanisms that have not …
Received 04 November 2009 08:33 UTC; Posted 04 November 2009
Posted to: Cancer, Genetics & Genomics, Molecular Cell Biology
Far-infrared rays control prostate cancer cells in vitro and in vivo
We introduce a new effective method to control hormone refractory prostate cancer cells by using an activated rubber/resin form (RB), far-infrared ray emitter, with or without sodium butyrate (SB)....
Received 20 March 2009 07:15 UTC; Posted 20 March 2009
Posted to: Cancer
Optimal control circuitry design for the digital p53 dynamics in cancer cell and apoptosis
Experimental work and theoretical models deduce a “digital” response of the p53 transcription factor when genomic integrity is damaged. The mutual influence of p53 and its antagonist, the Mdm2 onco…
Received 13 February 2009 00:02 UTC; Posted 17 February 2009
Posted to: Biotechnology, Cancer, Developmental Biology
Down-regulation of Survivin enhances sensitivity to BPR0L075 in human cancer cells via caspase-independent mechanisms
Background: BPR0L075 [6-methoxy-3-(3’,4’,5’-trimethoxy-benzoyl)-1H-indole] is a novel anti-cancer compound. It inhibits tubulin polymerization and induces mitochondrial-dependent apoptosis in vario…
Received 29 December 2008 09:16 UTC; Posted 29 December 2008
Posted to: Cancer
Genome-wide transcription analysis of interaction between the human macrophage and Mycobacterium tuberculosis during concurrent drug administration by conventional and novel methods
Targeted drug delivery to alveolar macrophages harboring Mycobacterium tuberculosis (Mtb) holds promise of high efficacy against pulmonary tuberculosis (TB). It was investigated whether inhalable m…
Received 31 October 2008 05:43 UTC; Posted 04 November 2008
Posted to: Pharmacology
Transforming growth factor-beta 1 (tgf-β1) induces angiogenesis through vascular endothelial growth factor (vegf)-mediated apoptosis
VEGF and TGF-β1 induce angiogenesis but have opposing effects on endothelial cells. VEGF protects endothelial cells from apoptosis; TGF-β1 induces apoptosis. We have previously shown that…
Received 02 April 2008 16:49 UTC; Posted 03 April 2008
Posted to: Cancer
Beneficial role of allicin from garlic in cervical cancer
Introduction: Cervical cancer remains a global health concern for females. Thus, in order to control cervical cancer, attempts are being made by researchers globally to somehow induce programmed ce…
Received 01 February 2008 12:21 UTC; Posted 01 February 2008
Posted to: Cancer, Molecular Cell Biology
Apoptotic gene expression in neuropathic pain
Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system…
Received 30 January 2008 15:13 UTC; Posted 30 January 2008
Posted to: Pharmacology
Reversal of an immunity associated plant cell death program by the growth regulator auxin
One form of plant immunity against pathogens involves a rapid host programmed cell death at the site of infection accompanied by resistance, termed the hypersensitive response (HR). Here it is show…
Received 18 November 2007 18:01 UTC; Posted 19 November 2007
Posted to: Biotechnology, Microbiology, Molecular Cell Biology, Plant Biology
Tumor necrosis factor and caspase in response to soluble or microparticle-incorporated drugs in Mycobacterium tuberculosis infection
We compared the effects of microparticles (MP) containig anti-tubercular drugs and those of the drugs themselves on the host macrophage (MΦ) response to infection with Mycobacterium tuberculosis H3…
Received 28 September 2007 17:12 UTC; Posted 30 September 2007
Posted to: Immunology, Pharmacology