Submissions tagged with annotation
(32 documents)
The Gene Ontology’s Reference Genome Project: A Unified Framework for Functional Annotation across Species
Complete functional annotation of genomes is a powerful tool for researchers; however, such annotation is a time-consuming task limited by the availability of experimental data. The function of gen…
Received 22 April 2009 22:47 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
GENCODE: Creating a Validated Manually Annotated Geneset for the Whole Human Genome
The Human and Vertebrate Analysis and Annotation (HAVANA) group at the Wellcome Trust Sanger Institute produced the manually annotated geneset for the Encyclopedia of DNA Elements (ENCODE) pilot pr…
Received 23 April 2009 10:51 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
The Eukaryotic Linear Motif Resource (ELM): Regulatory Sites in Proteins
Linear motifs are short and evolutionarily variable sequence patterns associated with particular functions often involving post-translational modifications, such as phosphorylation, acetylation, gl…
Received 23 April 2009 10:26 UTC; Posted 23 April 2009
Posted to: Bioinformatics
Worm Annotation in the UniProt Knowledgebase (UniProtKB)
The nematode worm, Caenorhabditis elegans, was the first multicellular organism to be sequenced. Its genome was published in 1998, providing an impetus for gene and protein annotation. Recently, ...
Received 23 April 2009 11:47 UTC; Posted 23 April 2009
Posted to: Bioinformatics
IMGT/Automat: the strategy for the annotation of human and mouse cDNA nucleotide sequences of IG and TR
The cDNA sequences of immunoglobulins (IG) and T cell receptors (TR) represent more than one half of the sequences in the IMGT® nucleotide database IMGT/LIGM-DB1 and 75% of them are from human …
Received 23 April 2009 13:49 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Immunology, Bioinformatics
The Gene Ontology Annotation (GOA) Database
The Gene Ontology (GO) is a well-established, structured vocabulary that has been successfully used for 10 years in the annotation of proteins. GO terms, created in consultation with the biology co…
Received 23 April 2009 10:42 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Cardiovascular Gene Ontology Annotation Initiative
Gene Ontology (GO) provides a controlled vocabulary, which is used by several groups around the world to provide functional annotation to proteins across a wide range of species (“www.geneontology….
Received 22 April 2009 13:32 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Terminizer – Assisting Mark-Up of Text Using Ontological Terms
We present a tool that automatically detects ontological terms in free text. Once candidate terms have been identified the results are displayed either overlaid on the original text or in a list or…
Received 22 April 2009 11:53 UTC; Posted 22 April 2009
Posted to: Bioinformatics
A Framework for BioCuration Workflows (part II)
This is the second part of the talk ‘A Framework for BioCuration Workflows’, given by Martin Krallinger from the Spanish National Cancer Research Centre at the ‘Text Mining for the BioCuration Work…
Received 22 April 2009 11:21 UTC; Posted 22 April 2009
Posted to: Bioinformatics
P-POD, The Princeton Protein Orthology Database, as a Tool for Identifying Gene Function
P-POD, the Princeton Protein Orthology Database, classifies proteins from model organisms and medically-important organisms into families of homologs and provides curated evidence from the literatu…
Received 21 April 2009 15:24 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
