Submissions tagged with UniProtKB
(12 documents)
The Relationship between the UniProt Knowledgebase (UniProtKB) and the IntAct Molecular Interaction Databases
IntAct provides a freely available, open source database system and analysis tools for protein interaction data. All interactions are derived from literature curation or direct user submission and …
Received 03 November 2009 16:55 UTC; Posted 10 November 2009
Posted to: Bioinformatics
Biocuration Workflow Catalogue
As the first phase of a knowledge engineering study of biocuration workflows, we performed a preliminary task-modeling exercise on seven separate bioinformatics systems. This involved constructing …
Received 13 May 2009 18:00 UTC; Posted 13 May 2009
Posted to: Bioinformatics
Automatisation in UniProtKB / Swiss-Prot Annotation: New Rules and Tools
The development of next generation sequencing technologies promises a massive increase in the rate of submission of new protein sequences to sequence databases such as the Universal Protein Resourc…
Received 04 May 2009 11:27 UTC; Posted 08 May 2009
Posted to: Bioinformatics
Standardization in UniProtKB/Swiss-Prot
Within the UniProt consortium, the UniProtKB/Swiss-Prot knowledge base provides the international community with a stable, comprehensive, fully classified, richly and accurately annotated protein s…
Received 04 May 2009 09:41 UTC; Posted 08 May 2009
Posted to: Bioinformatics
Reactome – a knowledgebase of human biological pathways
Reactome (http://www.reactome.org) is an expert-authored, peer-reviewed knowledgebase of human reactions and pathways that functions as a data mining resource and electron…
Received 29 April 2009 09:05 UTC; Posted 03 May 2009
Posted to: Chemistry, Genetics & Genomics, Immunology, Molecular Cell Biology, Bioinformatics
UniProt in RDF: Tackling Data Integration and Distributed Annotation with the Semantic Web
The UniProt knowledgebase (UniProtKB) is a comprehensive repository of protein sequence and annotation data. We collect information from the scientific literature and other databases and provide li…
Received 28 April 2009 13:14 UTC; Posted 28 April 2009
Posted to: Bioinformatics
Broadening Pfam Protein Sequence Annotations
Pfam is a database of conserved protein families or domains commonly used for genome annotation and sequence classification. It comprises two parts: (1) Pfam-A families, which are fully annotated a…
Received 28 April 2009 13:26 UTC; Posted 28 April 2009
Posted to: Bioinformatics
Worm Annotation in the UniProt Knowledgebase (UniProtKB)
The nematode worm, Caenorhabditis elegans, was the first multicellular organism to be sequenced. Its genome was published in 1998, providing an impetus for gene and protein annotation. Recently, ...
Received 23 April 2009 11:47 UTC; Posted 23 April 2009
Posted to: Bioinformatics
Xenopus and Zebrafish Annotation in the UniProt Knowledgebase (UniProtKB)
The African clawed frog Xenopus laevis and the zebrafish Danio rerio have both proved to be good model organisms for studying early vertebrate cellular and developmental biology. More recently, the…
Received 23 April 2009 10:30 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics
The Gene Ontology Annotation (GOA) Database
The Gene Ontology (GO) is a well-established, structured vocabulary that has been successfully used for 10 years in the annotation of proteins. GO terms, created in consultation with the biology co…
Received 23 April 2009 10:42 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Bioinformatics