Submissions tagged with Pharmacology
(5 documents)
IUPHAR-DB: An Expert-Curated, Peer-Reviewed Database of Receptors and Ion Channels
The International Union of Basic and Clinical Pharmacology database (IUPHAR-DB) integrates peer-reviewed pharmacological, chemical, genetic, functional and anatomical information on the 354 non-sen…
Received 07 May 2009 15:50 UTC; Posted 07 May 2009
Posted to: Pharmacology, Bioinformatics
Chronic cocaine enhances release of neuroprotective amino acid taurine: a microdialysis study
Cocaine inhibits high-affinity neurotransmitter uptake at the presynaptic nerve terminals to increase synaptic levels of dopamine, norepinephrine and serotonin1. This increase of synaptic dopamin…
Received 22 September 2008 19:49 UTC; Posted 24 September 2008
Posted to: Neuroscience, Pharmacology
Successful use of axonal transport for drug delivery by synthetic molecular vehicles
We report the use of axonal transport to achieve intraneural drug delivery. We constructed a novel tripartite complex of an axonal transport facilitator conjugated to a linker molecule bearing up t…
Received 06 August 2008 15:14 UTC; Posted 07 August 2008
Posted to: Biotechnology, Chemistry, Molecular Cell Biology, Neuroscience, Pharmacology
Application of the Sensory Contact Model for Pharmacological Studies under Simulated Clinical Conditions
The sensory contact model allows forming different psycho-pathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, cognition disturbances, anhedonia, addictiv…
Received 19 December 2007 07:27 UTC; Posted 19 December 2007
Posted to: Neuroscience, Pharmacology
Side effect profile prediction – Tackling Big Pharma’s worst nightmare at an early stage
This talk presents a method that predicts adverse side effects for molecules based on the chemical structure only. Also, targets for the compounds are predicted. Therefore it becomes possible to li…
Received 18 October 2007 21:10 UTC; Posted 23 October 2007
Posted to: Chemistry, Pharmacology, Bioinformatics
