Submissions tagged with Human
(10 documents)
Variation in PNPLA3 is associated with outcomes in alcoholic liver disease
Two recent genome-wide association studies have described associations of SNP variants in PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels in population based cohorts. We inves…
Received 05 October 2009 19:14 UTC; Posted 06 October 2009
Posted to: Genetics & Genomics
H-InvDB release 6, a comprehensive annotation resource for human genes and transcripts
H-Invitational Database (H-InvDB; http://www.h-invitational.jp/) is an integrated database of human genes and transcripts. By extensive analyses of all human transcr…
Received 14 May 2009 02:31 UTC; Posted 14 May 2009
Posted to: Genetics & Genomics, Bioinformatics, Evolutionary Biology
Reactome – a knowledgebase of human biological pathways
Reactome (http://www.reactome.org) is an expert-authored, peer-reviewed knowledgebase of human reactions and pathways that functions as a data mining resource and electron…
Received 29 April 2009 09:05 UTC; Posted 03 May 2009
Posted to: Chemistry, Genetics & Genomics, Immunology, Molecular Cell Biology, Bioinformatics
HGNC: The Why and How of Standardised Gene Nomenclature
The HUGO Gene Nomenclature Committee (HGNC) aims to approve a unique gene symbol and gene name for every human gene. Standardisation of gene symbols is necessary to allow researchers and curators …
Received 27 April 2009 11:12 UTC; Posted 28 April 2009
Posted to: Genetics & Genomics, Bioinformatics
IMGT/GENE-DB: genomic reference sequences for human and mouse IG and TR genes and alleles
The immunoglobulin (IG) and T cell receptor (TR) major loci span about 6 Megabases (Mb) of the human genome on chromosomes 2, 7, 14 and 22, and 9 Mb in mouse on chromosomes 6, 12, 13, 14 and 16. Th…
Received 23 April 2009 13:26 UTC; Posted 23 April 2009
Posted to: Genetics & Genomics, Immunology, Bioinformatics
Genome-wide association study identifies FUT8 and ESR2 as co-regulators of a bi-antennary N-linked glycan A2 (GlcNAc2Man3GlcNAc2) in human plasma proteins
HPLC analysis of N-glycans quantified levels of the biantennary glycan (A2) in plasma proteins of 924 individuals. Subsequent genome-wide association study (GWAS) using 317,503 single nucleotide po…
Received 10 February 2009 02:55 UTC; Posted 10 February 2009
Posted to: Genetics & Genomics, Molecular Cell Biology
Energy or chow, that’s a question: “two-bottle” may be more suitable than “one-bottle” in modeling nutritional obesity
Objective: To model nutritional obesity in rats with two-bottle-feeding method according to human eating feature. Design: Animals were grouped into control and model randomly according to the…
Received 27 November 2008 10:05 UTC; Posted 02 December 2008
Posted to: Neuroscience
Second-Hand Stress: Neurobiological Evidence for a Human Alarm Pheromone
Alarm pheromones are airborne chemical signals, released by an individual into the environment, which transmit warning of danger to conspecifics via olfaction. Using fMRI, we provide the first neur…
Received 24 November 2008 19:50 UTC; Posted 25 November 2008
Posted to: Neuroscience
Enhancing me – hope or hype?
Many people talk about human enhancement as if it is about to happen. Some suggest that it already has. To join in the debate you need to distinguish between social, personal and species enhancemen…
Received 15 August 2008 00:54 UTC; Posted 19 August 2008
Posted to: Biotechnology, Genetics & Genomics, Neuroscience
Ancient Trephinations in Neolithic People – Evidence for Stone Age Neurosurgery?
The authors present the case of a late neolithic skull (14C dating: 1940 calBC) found 1921 at Bölkendorf, 60 km north-easterly of Berlin. It shows a left frontal trephination (53×50 mm) and addit…
Received 21 February 2008 21:56 UTC; Posted 21 February 2008
Posted to: Ecology
