Submissions tagged with Genome Annotation
(7 documents)
Evolution of the Sequence Ontology terms and relationships
The Sequence Ontology is undergoing reform to meet the standards of the OBO Foundry. Here we report some of the incremental changes and improvements made to SO. We also propose new relationships to…
Received 28 July 2009 21:10 UTC; Posted 29 July 2009
Posted to: Bioinformatics
In silico analysis for the presence of HARDY an Arabidopsis drought tolerance DNA binding transcription factor product in chromosome 6 of Sorghum bicolor genome
Expression of the Arabidopsis HARDY (hrd) DNA binding transcription factor (555 bp present on chromosome 2) has been shown to increase WUE in rice by Karaba et al 2007 (PNAS, 104:15270–15275). We c…
Received 18 July 2009 04:04 UTC; Posted 20 July 2009
Posted to: Bioinformatics
Curation at the NCBI: Genomes, Genes, & Sequence Standards
The National Center for Biotechnology Information (NCBI) provides curation support for many genomes, and disseminates information in several resources including Entrez Gene, reference sequences (R…
Received 26 May 2009 16:13 UTC; Posted 27 May 2009
Posted to: Genetics & Genomics, Bioinformatics
Broadening Pfam Protein Sequence Annotations
Pfam is a database of conserved protein families or domains commonly used for genome annotation and sequence classification. It comprises two parts: (1) Pfam-A families, which are fully annotated a…
Received 28 April 2009 13:26 UTC; Posted 28 April 2009
Posted to: Bioinformatics
Manual annotation of the mouse genome: HAVANA and EUCOMM
The European Conditional Mouse Mutagenesis (EUCOMM) project aims to establish a mutant resource containing up to 13,000 conditional mouse mutations in C57BL/6N embryonic stem cells. As part of this…
Received 27 April 2009 09:12 UTC; Posted 27 April 2009
Posted to: Genetics & Genomics, Bioinformatics
WormBase – Nematode Biology and Genomes
WormBase is the major public online database resource for the Caenorhabditis research community. The database was developed primarily for the nematode C. elegans but expanded to host genomes an…
Received 22 April 2009 12:12 UTC; Posted 22 April 2009
Posted to: Genetics & Genomics, Bioinformatics
Decoding the Design Principles of Amino Acids and the Chemical Logic of Protein Sequences
That only 20 amino acids occur naturally accounting for the structural and functional diversity of proteins remains a mystery. We show here that this is a consequence of the action of a symmetry gr…
Received 30 July 2008 07:17 UTC; Posted 31 July 2008
Posted to: Chemistry, Bioinformatics