http://precedings.nature.com/tags/Fetal%20Heart%20rate Recently posted documents tagged with 'Fetal Heart rate' Nature Publishing Group en Nature Precedings http://precedings.nature.com/images/header_logo.gif http://precedings.nature.com http://dx.doi.org/10.1038/npre.2007.980.2 Recording of fetal heart rate via CTG monitoring has been routinely performed as an important part of antenatal and subpartum care for several decades. The current guidelines of the FIGO (ref1) recommend a normal range of the fetal heart rate from 110 to 150 bpm. However, there is no agreement in the medical community whether this is the correct range (ref2). We aim to address this question by computerized analysis (ref 3) of a high quality database (HQDb, ref 4) of about one billion electronically registered fetal heart rate measurements from about 10,000 pregnancies in three medical centres over seven years. In the present paper, we lay out a detailed analysis plan for this evidence-based project in the vein of the validation policy of the Sylvia Lawry Centre for Multiple Sclerosis Research (ref 5) with a split of the database into an exploratory part and a part reserved for validation. We will perform the analysis and the validation after publication of this plan in order to reduce the probability of publishing false positive research findings (ref 6-7). http://dx.doi.org/10.1038/npre.2007.980.2 Mon, 12 Nov 2007 16:48:34 UTC The Normal Fetal Heart Rate Study: Analysis Plan doi:10.1038/npre.2007.980.2 2007-11-12 Martin Daumer Nature Precedings 2007-11-12T16:48:34Z Manuscript Bioinformatics http://creativecommons.org/licenses/by/2.5/ http://dx.doi.org/10.1038/npre.2007.980.1 Recording of fetal heart rate via CTG monitoring has been routinely performed as an important part of antenatal and subpartum care for several decades. The current guidelines of the FIGO (ref1) recommend a normal range of the fetal heart rate from 110 to 150 bpm. However, there is no agreement in the medical community whether this is the correct range (ref2). We aim to address this question by computerized analysis (ref 3) of a high quality database (HQDb, ref 4) of about one billion electronically registered fetal heart rate measurements from about 10,000 pregnancies in three medical centres over seven years. In the present paper, we lay out a detailed analysis plan for this evidence-based project in the vein of the validation policy of the Sylvia Lawry Centre for Multiple Sclerosis Research (ref 5) with a split of the database into an exploratory part and a part reserved for validation. We will perform the analysis and the validation after publication of this plan in order to reduce the probability of publishing false positive research findings (ref 6-7). http://dx.doi.org/10.1038/npre.2007.980.1 Mon, 17 Sep 2007 12:48:48 UTC The Normal Fetal Heart Rate Study: Analysis Plan doi:10.1038/npre.2007.980.1 2007-09-17 Martin Daumer Nature Precedings 2007-09-17T12:48:48Z Manuscript Bioinformatics http://creativecommons.org/licenses/by/2.5/