Submissions tagged with Alzheimer
(2 documents)
5 votes
Altered cholesterol ester cycle in ex vivo skin fibroblasts from Alzheimer patients
Recent studies in both animal and cell models of Alzheimer’s disease (AD) indicated that sub-cellular cholesterol distribution seems to regulate amyloid-beta (Aβ) generation in the brain. In p…
Received 18 February 2008 17:15 UTC; Posted 19 February 2008
Posted to: Molecular Cell Biology, Neuroscience
3 votes
Changes in Cholesterol Metabolism in Peripheral Cells of Alzheimer Disease Patients and Their Relatives
Background. Previous epidemiological and experimental studies indicated cholesterol as a central player in Alzheimer disease (AD). Here, we utilized skin fibroblasts and PBMC as possible ex vivo m…
Received 23 October 2007 08:02 UTC; Posted 08 November 2007
Posted to: Molecular Cell Biology, Neuroscience
