Pharmacology
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MIF-AMPK cascades
Withdrawn for publication
Received 11 June 2009 21:04 UTC; Posted 12 June 2009
Posted to: Molecular Cell Biology, Pharmacology
Herbal Drugs in Mirror of Alzheimer’s Disease
Commercially available Ginkgo biloba leaf extracts may lack specificity as to the binding of copper and zinc ions in human cells. This might be the reason why Ginkgo extracts have no predictable an…
Received 11 June 2009 07:38 UTC; Posted 11 June 2009
Posted to: Biotechnology, Neuroscience, Pharmacology, Plant Biology
Design of selective peptide antibiotics by using the sequence moment concept
WithdrawnIncomplete data
Received 02 May 2009 08:02 UTC; Posted 04 May 2009
Posted to: Biotechnology, Pharmacology, Bioinformatics
Characteristics of Uremic Cardiomyopathy with Reversible Systolic Dysfunction
Background: There exists a sub group of patients with uremic cardiomyopathy who experience resolution of heart failure following hemodialysis. It has been hypothesized that these patients are fluid…
Received 29 April 2009 08:45 UTC; Posted 14 May 2009
Posted to: Chemistry, Pharmacology
Small Colony Variants and Senescent Bacteria
Small colony variants (SCVs) are bacterial subpopulation that grow slowly and form smaller colonies. They have been described for a wide range of bacterial species, but most extensively studied for…
Received 21 April 2009 14:40 UTC; Posted 22 April 2009
Posted to: Microbiology, Pharmacology
Preliminary results of a semi-empirical study on the structure and reactivity of the Paroxetine drug
Paroxetine is a widely consumed drug with antidepressant and anxiolytic activity prescribed in the treatment of related disorders, such as obsessive-compulsive disorder, panic fits, social phobias …
Received 08 April 2009 21:54 UTC; Posted 10 April 2009
Posted to: Chemistry, Pharmacology
Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids
The pKa estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program. Compound classes under…
Received 25 March 2009 17:24 UTC; Posted 26 March 2009
Posted to: Chemistry, Pharmacology, Earth & Environment
Rapid extinction of cocaine craving: toward a novel cue exposure therapy
Cocaine does not only evoke intense rewarding sensations but also induces craving for more cocaine. This latter effect is especially obvious in addicted individuals and is thought to contribute tog…
Received 25 March 2009 16:43 UTC; Posted 31 March 2009
Posted to: Neuroscience, Pharmacology
Glutathione (GSH) conjugates with dopamine (DA)-derived quinones to form reactive or non-reactive GSH-conjugates
In this study we demonstrate for the first time that GSH could rapidly conjugate with dopamine (DA)-derived DA-o-quinones without enzymatic catalysis to form short-lived intermediate GSH-conjugates…
Received 21 March 2009 11:03 UTC; Posted 23 March 2009
Posted to: Biotechnology, Chemistry, Neuroscience, Pharmacology
ADME/Tox WEB in silico predictions of longer chain perfluoroalkyl carboxylic acid pKa values are more accurate than other computational methods
Perfluoroalkyl carboxylates are contaminants whose environmental fate and toxicological effects are of broad interest within the academic, industrial, and governmental science and regulatory commun…
Received 09 March 2009 03:41 UTC; Posted 10 March 2009
Posted to: Chemistry, Pharmacology, Earth & Environment