Molecular Cell Biology
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Valid and efficient formula for free energy difference from nonequilibrium work
Atomic force microscopes and optical tweezers afford direct probe into the inner working of single biomolecules by mechanically unfolding them.1-15 Critical to the success of this type of probe i…
Received 26 May 2008 05:35 UTC; Posted 27 May 2008
Posted to: Chemistry, Molecular Cell Biology, Bioinformatics
A novel regulator of the p53-mediated mitochondrial apoptotic pathway
The p53 tumor suppressor protein induces apoptosis in response to genotoxic and environmental stress. Recent studies have revealed the existence of a transcription-independent mitochondrial p53 apo…
Received 15 May 2008 07:13 UTC; Posted 16 May 2008
Posted to: Cancer, Molecular Cell Biology
The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endot…
Received 14 May 2008 11:25 UTC; Posted 14 May 2008
Posted to: Molecular Cell Biology
Bio-Communication of Bacteria and its Evolutionary Interrelations to Natural Genome Editing Competences of Viruses
Communicative competences enable bacteria to develop, organise and coordinate rich social life with a great variety of behavioral patterns even in which they organise themselves like multicellular …
Received 13 May 2008 17:11 UTC; Posted 14 May 2008
Posted to: Molecular Cell Biology, Evolutionary Biology
An optimized energy potential can predict SH2 domain-peptide interactions
Peptide recognition modules (PRMs) are used throughout biology to mediate protein-protein interactions, and many PRMs are members of large protein domain families. Members of these families are of…
Received 12 May 2008 20:23 UTC; Posted 12 May 2008
Posted to: Molecular Cell Biology, Bioinformatics
Green Fluorescent Protein (GFP) in Vector Systems Played Sense Role of Epigenetic in Plants
The green fluorescent protein (GFP) of jellyfish (Aequorea victoria) has significant advantages over other reporter genes, because expression can be detected in living cells without any substrate…
Received 29 April 2008 20:38 UTC; Posted 30 April 2008
Posted to: Biotechnology, Molecular Cell Biology, Plant Biology
The Effect of a Reduced-Calorie Diet on alpha-2 Adrenergic Receptor Responsiveness in Abdominal Adipose Tissue in Obese Men During Exercise
There is at present an imperfect understanding of the effect of diet on availability of inhibitory receptors in fat cells during exercise among obese men. Objective: The purpose of this study…
Received 26 April 2008 04:55 UTC; Posted 28 April 2008
Posted to: Molecular Cell Biology
Findings From an Accelerated In Vivo Corrosion Model of Magnesium
In this article, we are presenting some findings of magnesium corrosion in an in vivo model. While there is consensus that subcutaneous bubbles will occur, it was found in our corrosion-accelerat…
Received 25 April 2008 12:56 UTC; Posted 28 April 2008
Posted to: Chemistry, Molecular Cell Biology
Overexpression of an isoform of AML1 in acute leukemia and its potential role in leukemogenesis
AML1/RUNX1 is a critical transcription factor in hematopoietic cell differentiation and proliferation. From the AML1 gene, at least three isoforms, AML1a, AML1b and AML1c, are produced thro…
Received 14 April 2008 01:44 UTC; Posted 14 April 2008
Posted to: Cancer, Molecular Cell Biology
Barlow-Hall in vitro Evolution Protocol
The Barlow-Hall method for in vitro evolution is a simple alternative to methods such as DNA shuffling and is particularly applicable to predicting the evolution of target genes in nature. This de…
Received 07 April 2008 21:49 UTC; Posted 08 April 2008
Posted to: Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology